National Institue of Health Ranking: 252/3181
Ninety Second Percentile

Research Funding for Fiscal Year 2005:

NIH $14,973,924
Federal (non-NIH) $3,035,556
Foundation $1,276,296
Industry $2,908,705
State $489,324
Other $69,537
Total $22,753,342

Research Fair:

On June 13, 2007 St. Luke's-Roosevelt hosted its first centerwide research fair. Forty-six posters were featured from 12 different training programs. Our thanks go to the three prestigious judges and all who participated.

Guest judges from prestigious institutions:

  • Dr. Sheldon Jacobson, Chair, Emergency Medicine, Mount Sinai School of Medicine
  • Dr. Neil Schluger, Chief, Pulmonary and Critical Care Medicine, Columbia College of Physicians and Surgeons
  • Dr. Robin Dibner, Vice Chair for Education, Lenox Hill Hospital and Chair of the Research Section of NY ACP
CONGRATULATIONS TO OUR WINNERS!!
  • 1st Prize: Leslie Tyrie, Dept of Surgery, "AneuMastat(R) Green Tea Extract Reduces Aneurysm Incidence in the Angiotensin II (AngII)-Induced Model of Abdominal Aortic Aneurysm (AAA) in the Wildtype C57BL6 Mouse" - $500
  • 2nd Prize: Ron G. Landmann, Dept of Surgery, "Identifying patients at risk for colon cancer nodal metastasis prior to surgery."- $300
  • 3rd Prize: Aslam Khan MD, Division of Cardiology, "Predicting Pulmonary Vein Isolation Responders by Using P-wave Duration" - $200

From Left to Right: Dibner, Landmann, Andrew Choi (accepting for Dr. Khan), Tyrie, Ethan Fried, MD Director of Graduate Medical Education, and Jacobson

Housestaff Publications:

Detecting and Assessing Macrophages In Vivo to Evaluate Atherosclerosis Non-Invasively Using Molecular MRI
Vardan Amirbekian , Michael Lipiniski , Karen Briley-Saebo , Smbat Amirbekian , Juan Aguinaldo , David Weinreb , Esad Vucic , Juan Frias , Fabien Hyafil , Venkatesh Mani , Edward Fisher, Zahi A Fayad
Manuscript accepted at PNAS

Barta SK,Yahalom J, Shia J, Hamlin PA.
Idiopathic cholestasis as a paraneoplastic phenomenon in Hodgkin's lymphoma.
Clin Lymphoma Myeloma. 2006 Jul;7(1):77-82.

Chacko M, Weinberg, J: Famvir for the treatment of herpes labialis, genital herpes, and herpes zoster. J Drugs Dermatol, submitted 2006

Seth Urestsky, Deborah R Cantales, Rawa Sarj i, Sripal Bangalore, Bette Kim, Sin-Sun Yao, Farooq A Chaudhry, Mark V Sherrid, St Luke’s-Roosevelt Hospital Center, New York, NY: AHA-International Stoke Conference 2007

Andrew D. Choi, B.A., Arti N. Shah, M.S., M.D., Jayanthi Koneru, M.D., Delia Cotiga, M.D., Tina C. Sichrovsky, M.D., Mark Sherrid, M.D., Suneet Mittal, M.D., and Jonathan S. Steinberg, M.D.
Efficacy of Pulmonary Vein Isolation in Patients with Hypertrophic Cardiomyopathy and Atrial Fibrillation- submitted to ACC 2007

 Ajay Shah, Rawa Sarji, Sripal Bangalore, Madhuri Devabhaktuni, Ramya Smitha Suryadevara, Donna Macmillan-Marrotti, Danny Pudpud, Jonathan S Steinberg, Joseph DeRose, Farooq A Chaudhry, St.Luke's- Roosevelt Hospital Center, New York, Inotropic Contractile Reserve is a Strong Predictor of Response to Cardiac Resynchronization Therapy. American Heart Association 2006

Delia Cotiga MD, Raffay Khan MD, Emad Aziz MD, Jayanthi Koneru MD, Walter Pierce MD, Arti N Shah, MD, Tina C Sichrovsky MD, Aysha Arshad MBBS, Suneet Mittal MD, Jonathan S. Steinberg MD.
Cardiac Resynchronization Therapy in Patients With Permanent Atrial Fibrillation: Why Don't Some Patients Benefit ? - submitted to ACC 2007

Gadolinium Mixed-Micelles: Effect of the amphiphile on in vitro and in vivo
efficacy in apolipoprotein E knockout mouse models of atherosclerosis

Karen C. Briley-Saebo, Vardan Amirbekian, Juan C. Frias, Venkatesh Mani, Juan Gilberto S Aguinaldo, Esad Vucic, Smbat Amirbekian, Zahi A. Fayad
Manuscript accepted at Magnetic Resonance in Medicine (MRM), June 2006

Ajay S Shah, Rawa Sarji, Nisrine Koteich, Sripal Bangalore, Xiaoqian Zhang, Shruti Shah, Siu-Sun Yao, Farooq A Chaudhry, St Lukes-Roosevelt Hospital Center, New York, NY: Incremental Prognostic Value of Transient Ischemic Left Ventricular Cavity Dilatation on Stress Echocardiography Over Historical, Clinical, Resting and Stress Echocardiographic Variables. American College of Cardiology 2006

Emad Aziz, Dan Musat, Sripal Bangalore,Joseph Mathew, Clenton Coleman, Stacy Vragel, Olivier Frankenberger, Eyal Herzog. The Impact of the Implementation of a Novel Critical
Pathway for Management of Patients with Acute Coronary Syndrome on House staff Education to improve Compliance with National Guidelines.” Abstract s ubmitted to AHA 7th Scientific Forum, March 2006.

Alikhani M, Alikhani Z, Boyd C, MacLellan CM, Raptis M, Liu R, Pischon N, Trackman PC, Gerstenfeld L and Graves DT. “ Advanced Glycation Endproducts Stimulate Osteoblast Apoptosis Via the MAP Kinase and Cytosolic Apoptotic Pathways.” Bone. 2006 Oct 23; [Epub ahead of print]

In vivo non invasive detection of macrophages using computed tomography and a specific contrast agent
Fabien Hyafil, Jean-Christophe Cornily, Johnathan E. Feig, Ronald Gordon, Esad Vucic, Vardan Amibekian, Edward A. Fisher, Valentin Fuster, Laurent J. Feldman, Zahi A. Fayad
Manuscript accepted at Nature Medicine

Ajay S Shah, Rawa Sarji, Danny Pudpud, Donna Macmillan-Marotti, Sripal Bangalore, Anand Haridas, Afam Onuora, Sandhya Balaram, Joseph DeRose, Jonathan S Steinberg, Farooq A Chaudhry, St Lukes-Roosevelt Hospital Center, New York, NY: Robotic Epicardial Cardiac Resynchronization is Superior to Endovascular Implantation in Promoting Reverse Remodeling. American College of Cardiology 2006

Jayanthi Koneru, MD, Lance W Weathers MD, Carl Braun MD.
St.Lukes-Roosevelt Hospital Center, New York.
"MELAS Syndrome - A Mitochondrial Disorder with Myriad Manifestations"-
winner of the NY ACP 2005 clinical vignette abstract competition.

Florescu D, Mathew J, Abdelnour S, Glyptis A, Braun C, and Polsky B , “Guillain-Barré Syndrome associated with an abnormal brain MRI following acute CMV infection in an immunocompetent patient.” Infectious Diseases Society of NY 12 th Annual Symposium, May 2005

Molecular imaging of macrophage activity in atherosclerotic plaques using bimodal PEG-micelles
Willem J.M. Mulder, Juan C. Frias, Karen C. Briley-Saboe, Juan Gilberto S.
Aguinaldo, Esad Vucic, Cheuk Tang, Patrick T.K. Chin, Klaas Nicolay, Gustav
J. Strijkers, Zahi A. Fayad
Manuscript submitted to Atherosclerosis, Thrombosis and Vascular Biology, ATVB

Ajay S Shah, Rawa Sarji, Sripal Bangalore, Eftekhari Hossein, Joseph DeRose, Jonathan S Steinberg, Farooq A Chaudhry, St Luke’s-Roosevelt Hospital Center, New York, NY: Inotropic Contractile Reserve is a Strong Predictor of Response to Cardiac Resynchronization Therapy. New York Echocardiographic Society 2006

Alikhani Z, Kukar A, Steinberg JS. “Brugada Syndrome; A case & Review” Journal of Hospital Physician.2006, In press.

Sripal Bangalore, Ajay S Shah, Rawa Sarji, Bilal Ayub, Madhuri Devabhaktuni, Siu-Sun Yao, Farooq A Chaudhry St Lukes-Roosevelt Hospital Center, New York, NY : Differential Prognosis Using Stress Echocardiography: Prediction of Myocardial Infarction Versus Cardiac Death. Winner of the Joan Barber Memorial Award, New York Echocardiographic Society 2005

Panjrath G, Messerli FH. β-Blockers for Primary Prevention in h Hypertension: Era Bygone? Progress in Cardiovascular Disease. 2006 Sep: 49(2): 76-87

Alikhani M, Alikhani Z, Graves DT. “FOXO1 functions as a master switch that regulates gene expression necessary for tumor necrosis factor-induced fibroblast apoptosis.” Journal of Biological Chemistry. 2005 Apr 1; 280(13):12096-102

Sripal Bangalore, Ajay S Shah, Rawa Sarji, Bilal Ayub, Madhuri Devabhaktuni, Siu-Sun Yao, Farooq A Chaudhry, St Lukes-Roosevelt Hospital Center, New York : Impact of Gender on Prognosis of Patients at Comparable Wall Motion Score Index and Ejection Fraction: A Stress Echo Study. Winner of the Joan Barber Memorial Award, New York Echocardiographic Society 2005

Begum S, Zhang XQ, Salciccioli L, Gohari A, Lazar JM. Chest Radiographic
Correlates of Serum BNP Levels. Chest Meeting Abstracts 2005; 128: 282S.

 Alikhani Z, Alikhani M, Boyd CM, Nagao K, Trackman PC, Graves DT. “Advanced glycation end products enhance expression of pro-apoptotic genes and stimulate fibroblast apoptosis through cytoplasmic and mitochondrial pathways.” Journal of Biological Chemistry. 2005 Apr 1;280(13):12087-95

Panjrath G, Narra K, Jain D. Myocardial perfusion imaging in a patient with chest pain. Journal of Nuclear Cardiology 2004; 11 (4) 514-516

Emad Aziz, Dan Musat, Delia Cotiga, Sripal Bangalore, Joseph Mathew, David Djebali, Jorge Silva , Ashraf Fawzy, Aysha Arshad, Jonathan Steinberg. “Complication Rate of Device Implantation in Patients with Impaired Renal Function.” Abstract s ubmitted to ACC Annual Scientific Session, March 2007 .

Valdiviezo C, Panjrath G, Hutter R, Fuster V, Badimon JJ. Nascent neovessels in lipid-rich neointima selectively express angiotensin receptor-1 and positively correlate with neointima size in a mouse model of arterial injury. Accepted for presentation at Scientific Sessions, American Heart Association, Dallas 2005

Lomax N, Wheeler H, Barta S et al. Do Patients accept and adhere to HAART? International Congress on Drug Therapy in HIV Infection, Glasgow, Scotland, Nov 2004 (Poster presentation)

Raza M, Panjrath G, Jain D. Extracardiac abnormalities on myocardial perfusion imaging. Journal of Nuclear Cardiology, March 2005; 12 (2) (Suppl)

 Panjrath G , Patel V, Narula N, Valdiviezo C, Narula J, Jain D. Potentiation of Doxorubicin Cardiotoxicity by Iron Loading in a Rodent Model. Journal of the American College of Cardiology 2005; 45 (1) 182 A (Supplement)

Bangalore S, Yao SS, Malik A, Shah A, Zhang XQ, Gopinath D, Uretsky S,
Chaudhry FA. Impact of Gender on Prognosis of Patients at Comparable Wall
Motion Score Index and Ejection Fraction: A Stress Echo Study. J Am Soc
Echocardiogr 2005; 18 (5); 560

Panjrath G.S,  Patel V., Narula N., Narula J., Jain D. Doxorubicin cardiotoxicity in a rodent model of iron overload: Assessment using Tc-99m-annexin. Journal of Nuclear Cardiology, March 2005 Vol. 12, Issue 2 (Suppl )

Hutter R, Valdiviezo C, Panjrath G, Sauter B, Carrick F, Fuster V, Badimon JJ. In Vivo Caspase-Inhibition Prevents Plaque Progression by Reducing Apoptosis and Tissue-Factor Expression in a Mouse Model of Chronic Atherosclerosis. Journal of the American College of Cardiology 2004

Emad Aziz , Dan Musat, Sripal Bangalore, Joseph Mathew, Clenton Coleman, Stacy Vragel, Olivier Frankenberger, Eyal Herzog. “Impact of a Novel Critical Pathway for the Management of Acute Coronary Syndrome leads to markedly improved Compliance with Guidelines and decreased Angina Symptoms at 12-month follow-up.” Abstract a ccepted to ACC 2006 as Oral Presentation.

Hutter R, Valdiviezo C, Sauter B, Corti R, Panjrath G, Fuster V, Badimon JJ. Evidence for Hypoxia and HIF-1-alpha mediated VEGF Expression in Lipid-Rich Plaque Macrophages as Link between Inflammation and Angiogenesis. Journal of the American College of Cardiology 2004

MacMillan MR, Jain D, Panjrath GS, Doddamani S, Vannan M, Rees MR. Measurement of myocardial infarct mass using Magnetic Resonance Imaging. European Society of Cardiac Radiology, Berlin October 2003

Panjrath G, Hartung D, Petrov A, Narula N, Patel V, Liu Z, Vannan M, Narula J, Jain D. Detection of doxorubicin induced myocardial apoptosis using Tc-99m-Annexin imaging. Journal of Nuclear Cardiology 2003;10 (1): S75(Abstract)

Kotsali P, Barta SK, Teruya-Feldstein J, Hamlin PA, Filippa DA: Primary
lung lymphomas: A clinicopathologic analysis of 61 cases, focusing on
immunophenotype, cytogenetics and molecular genetics. Poster presentation at
The United States and Canadian Academy of Pathology Annual Meeting
March 24 - March 30, 2007, San Diego, CA

Emad Aziz, Dan Musat, Delia Cotiga, Sripal Bangalore, Joseph Mathew, David Djebali, Jorge Silva , Ashraf Fawzy, Aysha Arshad, Jonathan Steinberg. “Complication Rate of Device Implantation in Patients with Impaired Renal Function.” Abstract s ubmitted to ACC Annual Scientific Session, March 2007 .

Yang WC, Mathew J, Velcich A, Edelman W, Kucherlapati R, Lipkin M, Yang K, and Augenlicht LH, “Targeted Inactivation of the p21 WAF1/cip1 Gene Enhances Apc-initiated Tumor-promoting Activity of a Western-Style High-Risk Diet by Altering Cell Maturation in the Intestinal Mucosa.” Cancer Research61, 565-569, January 2001

 Yang WC, Mathew J, Velcich A, Edelman W, Kucherlapati R, Lipkin M, Yang K, and Augenlicht LH, “Role of p21 Waf1/Cip1 in Inhibition and Promotion of Intestinal Tumors by Sulindac in Apc1638 Mice.” Proceedings of the AACR 42, March 2001

Panjrath G, Messerli FH. β-Blockers for Primary Prevention in h Hypertension: Era Bygone? Progress in Cardiovascular Disease. 2006 Sep: 49(2): 76-87

Subash HS, Gibikote SV, David T, Rose A, Swaroop P, Cherian AM
Abdominal tuberculosis affecting lesser omentum . J Assoc Physicians India.2001 Aug 49:848-9.Multiple Antibiotic Resistance of E. coli Isolated from Renal Transplant Patients with Urinary Tract Infection. Presented at World Transplant Congress (WTC), Boston, July 2006

Panjrath G , Jain D. Monitoring Chemotherapy Induced Cardiotoxicity: Role of Cardiac Nuclear Imaging. Journal of Nuclear Cardiology. 2006 Jun;13(3):415-426.

Pendyala S, Hu Z, Du J, Mitch WE.
Phosphatidyl 3-kinase is the Major Signalling Pathway Controlling Muscle Mass by Preventing Protein Degradation and Enhancing Regeneration
Presented at 38th American Society of Nephrology (ASN) Annual Meeting

Raza M, Meesala M, Panjrath G, Ghanbarania A, Jain D.Abnormal photopenic Area on Nuclear Perfusion Imaging., Journal of Nuclear Cardiology 2005 9 (12) 607-09

Bangalore S, Vragel S , Panjrath G, Parkar S, Messerli FH. Calcium Channel Antagonists Reduce the Risk of Stroke in Patients with Hypertension and Coronary Artery Disease: A Meta-Analysis. Accepted for presentation; Scientific Sessions of American Heart Association 2006

Panjrath G ,Jain D. Alteration in Iron Kinetics May Contribute to Doxorubicin Cardiotoxicity. Journal of the American College of Cardiology, March 2006

Bangalore S, Kamalakkannan G, Panjrath G, Messerli FH. Fixed-Dose Combination Improves Medication Compliance: A Meta-Analysis. Journal of Clinical Hypertension May 2006 Vol 8 (5) suppl A

Padder T, Kantharia B, PanjrathG et al; Complete device removal together with reimplantation of a new device is the optimum management of infected pacemaker and ICD leads. European Heart Journal 2002; 4:665 Abst. Suppl

Rice JC, Peng T, Kuo YF, Pendyala S, Simmons L, Boughton J, Ishihara K, Nowicki K, Nowicki S.
Renal Allograft Injury Is Associated with Urinary Tract Infection Caused by Escherichia coli Bearing Adherence Factors
Presentation at World Transplant Congress (WTC), Boston, July 2006

Iwata M, Silva Enciso JE, Cowling RT Greenberg BH. Regulatory
Mechanisms of Ectodomain Cleavage of Angiotensin-Converting Enzyme 2.
J Card Fail. 2006; Presented at the 10th Annual Scientific Meeting of the Heart Failure Society of America for the Jay N. Cohn New Investigator Award

Sripal Bangalore, Devi Gopinath, Rabia Arshad, Jorge Silva, et al.
Predictors of Mortality in the Setting of a Normal Stress Echocardiography.
Presented at the American Society of Echocardiography, June, 2006, Baltimore